See cook's science Cochinita Pibil - grill + sous vide
cook's science The Science of Pork Shoulder
conversion of connective tissue protein collagen to gelatin results in tender meat
starting at 140 deg the triple strand collagen unwinds to form 3 strands of gelatin
experiment - sous vide 40 gram portions and recorded time to gelatinize and moisture loss
140 deg requires 31 hr with 29.8% moisture loss
158 deg requires 16 hr with 33.1% moisture loss
176 deg requires 7 hr with 35.9% moisture loss
194 deg requires 2 hr with 37.5% moisture loss